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140 nghiên cứu chứng minh vaccine không có mối liên hệ correlation với tự kỷ

vaccine

Hôm nay mình bận nên các bạn đọc chơi danh sách 140 nghiên cứu chứng minh vaccine không có mối liên hệ correlation với tự kỷ chứ đừng có nói đến causation.

Đây là những nghiên cứu đã được peer-review và được đăng trên các tạp chí chuyên ngành uy tín. Trong đó có những nghiên cứu với cỡ mẫu lên đến hàng triệu đứa trẻ.

Tuy nhiên, theo một bạn antivax có vào đây comment trong một bài viết của mình thì tất cả các nghiên cứu này đều không chính xác vì việc sửa số liệu rất dễ dàng và tất cả các nhà nghiên cứu đều bị mua chuộc bởi các hãng dược. Duy chỉ có một vài nghiên cứu độc lập được đăng trong cuốn sách của bà lang băm vi lượng đồng căn Suzanne Humphrey là chính xác thôi. Tuy nhiên, khi mình hỏi vì sao bạn ấy biết và bằng chứng đâu thì được cho biết rằng bạn ấy biết như vậy là vì niềm tin. Có lẽ đây cũng là cách suy nghĩ chung của cộng đồng antivax.

Mình cũng không rõ là cần phải làm nghiên cứu đến mức nào nữa thì mới vừa lòng các bạn antivax.

Để hiểu hơn về correlation và causation, các bạn có thể đọc bài viết này của mình: ADVERSE REACTION

Còn đây là danh sách 140 nghiên cứu mà mình nói đến ở trên:

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32. DeStefano F, Thompson WW. MMR vaccination and autism: is there a link? Expert Opin Drug Saf. 2002 Jul;1(2):115-20. Review. PubMed PMID: 12904145.

33. DeStefano F, Chen RT. Negative association between MMR and autism. Lancet. 1999 Jun 12;353(9169):1987-8. PubMed PMID: 10376608.

34. DeStefano F, Chen RT. Autism and measles-mumps-rubella vaccination: controversy laid to rest? CNS Drugs. 2001;15(11):831-7. Review. PubMed PMID: 11700148.

35. Di Pasquale A, Bonanni P, Garçon N, Stanberry LR, El-Hodhod M, Tavares Da Silva F. Vaccine safety evaluation: Practical aspects in assessing benefits and risks. Vaccine. 2016 Nov 8. pii: S0264-410X(16)30974-4. doi: 10.1016/j.vaccine.2016.10.039. [Epub ahead of print] PubMed PMID: 27836435.

36. D’Souza J, Todd T. Measles-mumps-rubella vaccine and the development of autism or inflammatory bowel disease: the controversy should end. J Pediatr Pharmacol Ther. 2003 Jul;8(3):187-99. doi: 10.5863/1551-6776-8.3.187. PubMed PMID: 23118678; PubMed Central PMCID: PMC3469143.

37. D’Souza Y, Fombonne E, Ward BJ. No evidence of persisting measles virus in peripheral blood mononuclear cells from children with autism spectrum disorder. Pediatrics. 2006 Oct;118(4):1664-75. Erratum in: Pediatrics. 2006 Dec;118(6):2608. PubMed PMID: 17015560.

38. Doja A, Roberts W. Immunizations and autism: a review of the literature. Can J Neurol Sci. 2006 Nov;33(4):341-6. Review. PubMed PMID: 17168158.

39. Elliman D, Bedford H. MMR: where are we now? Arch Dis Child. 2007 Dec;92(12):1055-7. Epub 2007 Jul 11. Review. PubMed PMID: 17626143; PubMed Central PMCID: PMC2066086.

40. Farrington CP, Miller E, Taylor B. MMR and autism: further evidence against a causal association. Vaccine. 2001 Jun 14;19(27):3632-5. PubMed PMID: 11395196.

41. Fitzpatrick M. The end of the road for the campaign against MMR. Br J Gen Pract. 2007 Aug;57(541):679. PubMed PMID: 17688775; PubMed Central PMCID: PMC2099687.

42. Fombonne E, Chakrabarti S. No evidence for a new variant of measles-mumps-rubella-induced autism. Pediatrics. 2001 Oct;108(4):E58. PubMed PMID: 11581466.

43. Fombonne E, Zakarian R, Bennett A, Meng L, McLean-Heywood D. Pervasive developmental disorders in Montreal, Quebec, Canada: prevalence and links with immunizations. Pediatrics. 2006 Jul;118(1):e139-50. PubMed PMID: 16818529.

44. Gadad BS, Lia W, Yazdani U, Grady S, Johnson T, Hammond J, Gunn G, Curtis B, English C, Yutuc V, Ferrier C, Sackett GP, Marti N, Young K, Lewiston L, German DC. Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology. PNAS; Sept 2015. doi: 10.1073/pnas.1500968112.

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48. Glasper EA. New evidence reaffirms the safety of the MMR vaccine. Br J Nurs. 2002 Jun 27-Jul 10;11(12):794. PubMed PMID: 12131827.

49. Glickman G, Harrison E, Dobkins K. Vaccination Rates among Younger Siblings of Children with Autism. N Engl J Med. 2017 Sep 14;377(11):1099-1101. doi: 10.1056/NEJMc1708223. PubMed PMID: 28902586.

50. Goin-Kochel RP, Mire SS, Dempsey AG, Fein RH, Guffey D, Minard CG, Cunningham RM, Sahni LC, Boom JA. Parental report of vaccine receipt in children with autism spectrum disorder: Do rates differ by pattern of ASD onset? Vaccine. 2016 Mar 8;34(11):1335-42. doi: 10.1016/j.vaccine.2016.02.008. Epub 2016 Feb 8. PubMed PMID: 26868082.

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66. Jefferson T, Rudin M, Di Pietrantonj C. Adverse events after immunisation with aluminium-containing DTP vaccines: systematic review of the evidence. Lancet Infect Dis. 2004 Feb;4(2):84-90. Review. PubMed PMID: 14871632.

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68. Jick H, Kaye JA. Epidemiology and possible causes of autism. Pharmacotherapy. 2003 Dec;23(12):1524-30. Erratum in: Pharmacotherapy. 2004;24(4):following table of contents. PubMed PMID: 14695031.

69. Kaye JA, del Mar Melero-Montes M, Jick H. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis. BMJ. 2001 Feb 24;322(7284):460-3. PubMed PMID: 11222420; PubMed Central PMCID: PMC26561.

70. King BH. Promising Forecast for Autism Spectrum Disorders. JAMA. 2015 Apr 21;313(15):1518-1519. doi: 10.1001/jama.2015.2628. PubMed PMID: 25898047.

71. Klein KC, Diehl EB. Relationship between MMR vaccine and autism. Ann Pharmacother. 2004 Jul-Aug;38(7-8):1297-300. Epub 2004 Jun 1. Review. PubMed PMID: 15173555.

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77. Madsen KM, Lauritsen MB, Pedersen CB, Thorsen P, Plesner AM, Andersen PH, Mortensen PB. Thimerosal and the occurrence of autism: negative ecological evidence from Danish population-based data. Pediatrics. 2003 Sep;112(3 Pt 1):604-6. PubMed PMID: 12949291.

78. Madsen KM, Vestergaard M. MMR vaccination and autism : what is the evidence for a causal association? Drug Saf. 2004;27(12):831-40. Review. PubMed PMID: 15366972.

79. Mäkelä A, Nuorti JP, Peltola H. Neurologic disorders after measles-mumps-rubella vaccination. Pediatrics. 2002 Nov;110(5):957-63. PubMed PMID: 12415036.

80. Maglione MA, Das L, Raaen L, Smith A, Chari R, Newberry S, Shanman R, Perry T, Goetz MB, Gidengil C. Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review. Pediatrics; 2014 July 1 (published online). doi: 10.1542/peds.2014-1079

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82. Marwick C. US report finds no link between MMR and autism. BMJ. 2001 May 5;322(7294):1083. PubMed PMID: 11337432; PubMed Central PMCID: PMC1120232.

83. Meadows M. IOM report: no link between vaccines and autism. FDA Consum. 2004 Sep-Oct;38(5):18-9. PubMed PMID: 15595144.

84. Meilleur AA, Fombonne E. Regression of language and non-language skills in pervasive developmental disorders. J Intellect Disabil Res. 2009 Feb;53(2):115-24. doi: 10.1111/j.1365-2788.2008.01134.x. Epub 2008 Nov 27. PubMed PMID: 19054269.

85. Miller E. Measles-mumps-rubella vaccine and the development of autism. Semin Pediatr Infect Dis. 2003 Jul;14(3):199-206. Review. PubMed PMID: 12913832.

86. Miller E, Andrews N, Grant A, Stowe J, Taylor B. No evidence of an association between MMR vaccine and gait disturbance. Arch Dis Child. 2005 Mar;90(3):292-6. PubMed PMID: 15723921; PubMed Central PMCID: PMC1720314.

87. Miller L, Reynolds J. Autism and vaccination-the current evidence. J Spec Pediatr Nurs. 2009 Jul;14(3):166-72. doi: 10.1111/j.1744-6155.2009.00194.x. Review. PubMed PMID: 19614825.

88. Morris G, Puri BK, Frye RE, Maes M. The Putative Role of Environmental Mercury in the Pathogenesis and Pathophysiology of Autism Spectrum Disorders and Subtypes. Mol Neurobiol. 2017 Jul 22. doi: 10.1007/s12035-017-0692-2. [Epub ahead of print] Review. PubMed PMID: 28733900.

89. Motta M, Callaghan T, Sylvester S. Knowing less but presuming more: Dunning-Kruger effects and the endorsement of anti-vaccine policy attitudes. Soc Sci Med. 2018 Aug;211:274-281. doi: 10.1016/j.socscimed.2018.06.032. Epub 2018 Jun 25. PubMed PMID: 29966822.

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92. Mrozek-Budzyn D, Kiełtyka A, Majewska R. [Lack of association between MMR vaccination and the incidence of autism in children: a case-control study]. Przegl Epidemiol. 2009;63(1):107-12. Polish. PubMed PMID: 19522237.

93. Mrozek-Budzyn D, Majewska R, Kiełtyka A, Augustyniak M. [Lack of association between thimerosal-containing vaccines and autism].Przegl Epidemiol. 2011;65(3):491-5. Polish. PubMed PMID: 22184954.

94. Mrozek-Budzyn D, Majewska R, Kiełtyka A. Early exposure to thimerosal-containing vaccines and children’s cognitive development. A 9-year prospective birth cohort study in Poland. Eur J Pediatr. 2015 Mar;174(3):383-91. doi: 10.1007/s00431-014-2412-5. Epub 2014 Sep 5. PubMed PMID: 25185528; PubMed Central PMCID: PMC4334107.

95. Muhle R, Trentacoste SV, Rapin I. The genetics of autism. Pediatrics. 2004 May;113(5):e472-86. Review. PubMed PMID: 15121991.

96. Nelson KB, Bauman ML. Thimerosal and autism? Pediatrics. 2003 Mar;111(3):674-9. Review. PubMed PMID: 12612255.

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98. Offit PA. Vaccines and autism in primate model. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12236-7. doi: 10.1073/pnas.1516574112. Epub 2015 Sep 28. PubMed PMID: 26417097; PubMed Central PMCID: PMC4603512.

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